Spontaneous withdrawal experiment is a behavioral experiment based on the observation of withdrawal symptoms in animals after natural withdrawal of drugs. Its core purpose is to evaluate the degree of drug dependence and the occurrence and development of withdrawal symptoms. It is widely used in the study of the dependence mechanism of addictive substances and the evaluation of withdrawal intervention effects.
By repeatedly administering drugs to induce stable drug dependence in animals, and then stopping the administration, the spontaneous withdrawal behavior and physiological changes of animals are continuously observed and recorded without any withdrawal inducing drug intervention. By quantifying the severity and duration of withdrawal symptoms, the intensity of drug dependence and the natural progression of withdrawal reactions are reflected.