In Vivo SOA Rat/Mouse Models_上海瀚枢生物医药有限公司

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In Vivo SOA Rat/Mouse Models

The SOA rat/mouse model is used to evaluate the brain penetration level of candidate drugs. Specifically, animal brain tissue and plasma samples are collected at each preset pharmacokinetic (PK) time point to obtain preliminary brain and plasma PK data, as well as the ratio of the drug concentration in the brain to that in plasma (i.e., Kp), which is used to determine the brain penetration ability of the compound.

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