Non clinical drug dependence evaluation_上海瀚枢生物医药有限公司

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CNS Disease

Mental Illness

Depression Disorder

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Pharmacokinetics (PK)

Ex Vivo P-gp / BCRP Substrate Assessment System

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Human Deried Stem Cell And Organoids

iPS Cell-Derived Differentiated Cells

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Platfrom

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In Vitro Immunological Activity Evaluation of TCE Drugs

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Front Page > Service & Platfroms > CNS Safety Pharmacology > Non clinical drug dependence evaluation
CNS Safety Pharmacology
Non clinical drug dependence evaluation

CNS targets related to abuse/dependence:

- Opioids / DA / 5-HT / GABA / NMDA

- Receptors, transporters, etc


Mental dependence:

- Self administration experiment (rats)

- Conditional location preference experiment (rats)


Physical dependence:

- Natural withdrawal

- Urge withdrawal