The bilateral common carotid artery stenosis (BCAS) method induces bilateral common carotid artery (CCA) occlusion by placing partially occlusive microcoils around the carotid arteries. The diameter of the microcoils can affect the severity of the occlusion.
BCAS can induce cerebral white matter lesions, and the severity of these lesions is closely related to the degree of cerebral hypoperfusion. Therefore, the BCAS model is mainly characterized by spatial working memory impairment.
