The open field test (OFT) evaluates both "anxiety-like behaviors" and "spontaneous activity" of mice or rats by observing their spontaneous movements and exploratory behaviors in a novel, open arena.
- The higher the anxiety level of the animal, the shorter the time it stays in the central area.
- Fewer entries from the peripheral area to the central area indicate higher anxiety.
- A shorter total distance traveled in the central area indicates higher anxiety.
